The development of United States (US) foreign policy has continued to experience significant changes in recent years, influenced by global geopolitical dynamics. One of the main focuses is China’s rise as a global power. Under President Joe Biden’s administration, the US is trying to overcome the challenges posed by China’s ambitions, both in the Indo-Pacific region and in the global scenario. Initiatives such as AUKUS—a security agreement between Australia, the UK and the US—are strategic steps in forming alliances to balance power in the region. Apart from that, the US is also strengthening partnerships with countries in ASEAN and holding joint military exercises to increase readiness and cooperation. High-level diplomatic visits as well as investment in infrastructure projects in developing countries are part of the strategy to deepen ties. On the other hand, US foreign policy also focuses on the issue of climate change. The Biden administration rejoined the Paris Agreement and committed to significantly reducing greenhouse gas emissions. Environmental diplomacy is now a priority, with efforts to lead global initiatives to tackle climate change and encourage other countries to do the same. Involvement in multilateral forums, such as COP26, shows that the US wants to be a pioneer in environmental protection efforts. Another important thing is the US relationship with Russia. In the context of the conflict in Ukraine, the US provides military and economic support to help Ukraine maintain its sovereignty. The sanctions imposed on Russia show that the US is committed to responding to aggression. However, this approach faces challenges, considering the complexity of existing bilateral relations. In addition, the US continues to pay attention to the situation in the Middle East. Normalization agreements between Israel and several Arab countries have changed the geopolitical landscape, and the US has played a role in encouraging dialogue between the parties involved. This policy includes an emphasis on stability and the establishment of a two-state solution to the Israeli-Palestinian conflict, although challenges remain enormous. US foreign policy is also adapting to developments in technology and cybersecurity. The threat of cyberattacks, especially from countries such as China and Russia, is pushing the US to increase its defensive capabilities. Cooperation with allies in sharing intelligence and technology is an important step to increase national resilience. Furthermore, the US is facing challenges related to immigration and human rights protection. The policies implemented seek to improve the situation in migrants’ countries of origin, although moments of tension on the US-Mexico border often color public debate. The emphasis on cross-border cooperation in addressing the root causes of the problem is part of a broader strategy. Overall, developments in US foreign policy demonstrate the need to respect increasingly complex global dynamics. Integration between national security needs, international partnerships, and humanitarian and environmental issues is key to shaping effective and sustainable policy directions. This holistic approach will be a test for the US to maintain its position as a global leader in a changing world.